Abstract: “The effect of three plant latices on some pathogenic bacteria, dermatophytes and phytopathogenic fungi, and two medically important species of molusca as well were studied. Trials for detection of the active compounds and/or enzymes in plant latex responsible for the antimicrobial activities were also carried out. The results revealed that the three plant latices have good antimicrobial activities on Pseudomonas aeruginosa, Escherichia coli, Trichophyton rubrum and Chrysosporium tropicum. Latex of Ficus nitida was the most effective against both bacterial and fungal species. Phytochemical analyses revealed the presence of several active compounds (glycosides, terpenoids and tannins) in the three plant latices, (saponins) in Euphorbia pulcherrima and Ficus elastica, (phenolic compounds and alkaloids) in E. pulcherrima and F. nitida, (flavonoids) in only F. nitida latex. The serum fraction of latex from both E. pulcherrima and F. nitida had protease, lipase, chitinase and cellulases (C1”

Keywords: Euphorbiaceae, Asclepiadaceae, Moraceae, Asteraceae