Abstract: “The aim of the study was to provide some evidences for reliability and validity of the WHOQoL-BREF questionnaire - Farsi version in Iranian cancer patients. This descriptive correlational study was conducted in 2013 in which 198 cancer patients were conveniently recruited. The Cronbach’s alpha values for patients’ responses were 0.84, 0.75, 0.69, and 0.77, for physical, psychological, social relationship and environmental domains, respectively. Cronbach alpha values of patients QoL domain scores were above the acceptable level of 0.70. Most questions (21/24 or 88 percent) showed the highest correlations with domains to which they generally assigned supporting the for domain structure of the questionnaire. Findings of psychometric testing were generally promising indicating that the WHOQoL-BREF questionnaire was an appropriate tool to use in the clinical area of cancer patients.”

Keywords: WHOQoL-BREF questionnaire, Psychometric testing, oncology patients, Quality of Life,