Abstract: “We developed biosensors in which the detection element is an oligonucleotide -an aptamer- obtained through a combinatorial process. We characterized aptamers specific for different biomarkers. They can be integrated into different devices, allowing their use either in a grafted format or in solution. We developped a multiplex assay signaling the presence of nucleoside derivatives by either surface plasmon resonance or fluorescence anisotropy.”

Keywords: biosensor, oligonucleotide, aptamer, SPR, fluorescence, pollutant