Abstract: “Adverse childhood exposure has been discovered might alter physiological processes such as cardiovascular stress response. When the body is in a stressful condition, it triggers two primary systems that are particularly involved in adapting the body to the stress: the Autonomic Nervous System (ANS) and the Hypothalamic-Pituitary-Adrenocorticol (HPA) axis. To detect the altered stress response, biomarkers that represent both systems ANS and HPA are proposed. Among the available biomarkers, Heart Rate Variability (HRV) has been proven as a powerful biomarker that represents ANS. Meanwhile, salivary cortisol has been suggested as a biomarker that reflects the HPA. This study will investigate the stress response on individual who have had adverse childhood experience and no adverse childhood experience by using HRV and salivary cortisol. Electrocardiograph and salivary cortisol were collected from 23 healthy participants (age, 19 to 23 years old), 12 participants who had adverse childhood”

Keywords: stress, heart rate variability, cortisol, PASAT, children, signal processing