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MISSING VALUE ESTIMATION IN DNA MICROARRAY – A FUZZY APPROACH

Published In: INTERNATIONAL CONFERENCE ON ADVANCES IN COMPUTER SCIENCE AND ELECTRONICS ENGINEERING
Author(s): KASHINATH DEY , SUJAY SAHA , SUMIT CHAKRABORTY

Abstract: DNA microarray technology which is used in molecular biology, allows for the observation of expression levels of thousands of genes under a variety of conditions. The analysis of microarray data has been successfully applied in a number of studies over a broad range of biological disciplines. Now it is very unfortunate that various microarray experiments generate data sets containing missing values. Since most of the algorithms for gene expression analysis require a complete gene array as input, the missing values need to estimate. The methods exist for estimating missing values are like KNNimpute, SVDimpute, LLSimpute, LLS-SVDimpute etc. In this paper we present a new fuzzy technique Fuzzy Difference Vector Impute (FDVimpute) for estimating missing values in a DNA microarray

  • Publication Date: 03-Feb-2020
  • DOI: 10.15224/978-981-07-1403-1-214
  • Views: 0
  • Downloads: 0

MISSING VALUE ESTIMATION IN DNA MICROARRAY – A FUZZY APPROACH

Published In: INTERNATIONAL CONFERENCE ON ADVANCES IN COMPUTER SCIENCE AND ELECTRONICS ENGINEERING
Author(s): KASHINATH DEY , SUJAY SAHA , SUMIT CHAKRABORTY

Abstract: DNA microarray technology which is used in molecular biology, allows for the observation of expression levels of thousands of genes under a variety of conditions. The analysis of microarray data has been successfully applied in a number of studies over a broad range of biological disciplines. Now it is very unfortunate that various microarray experiments generate data sets containing missing values. Since most of the algorithms for gene expression analysis require a complete gene array as input, the missing values need to estimate. The methods exist for estimating missing values are like KNNimpute, SVDimpute, LLSimpute, LLS-SVDimpute etc. In this paper we present a new fuzzy technique Fuzzy Difference Vector Impute (FDVimpute) for estimating missing values in a DNA microarray

  • Publication Date: 03-Feb-2020
  • DOI: 10.15224/978-981-07-1403-1-214
  • Views: 0
  • Downloads: 0